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乙胺丁醇对眼部的毒性反应

发布时间:2010-09-06 来源:原创文章 作者:本站编辑 " ["prev"]=> object(app\common\model\Article)#4 (34) { ["autoWriteTimestamp":protected]=> bool(true) ["insert":protected]=> array(1) { [0]=> string(7) "site_id" } ["connection":protected]=> array(0) { } ["parent":protected]=> NULL ["query":protected]=> NULL ["name":protected]=> string(7) "Article" ["table":protected]=> NULL ["class":protected]=> string(24) "app\common\model\Article" ["error":protected]=> NULL ["validate":protected]=> NULL ["pk":protected]=> NULL ["field":protected]=> array(0) { } ["except":protected]=> array(0) { } ["disuse":protected]=> array(0) { } ["readonly":protected]=> array(0) { } ["visible":protected]=> array(0) { } ["hidden":protected]=> array(0) { } ["append":protected]=> array(0) { } ["data":protected]=> array(29) { ["id"]=> int(1149) ["site_id"]=> int(1) ["type_id"]=> int(42) ["title"]=> string(30) "患痢疾饮食要注意哪些" ["subtitle"]=> string(0) "" ["shorttitle"]=> string(0) "" ["color"]=> string(0) "" ["img"]=> string(0) "" ["url"]=> 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乙胺丁醇是一种常用的、有效的抗结核药物,但也可造成药物性医源病,尤其是眼部的表现。
  主要毒性反应是对视神经的损害,表现为视敏感度下降、中心暗点、绿色盲。
  具体的中毒表现为:
  1、轴性视神经类型:视神经中央纤维损害,中心视力下降,出现中心暗点和各绿色觉丧失。
  2、轴旁型视神经类型:视神经周围纤维受损,中心视力好,色觉正常,唯有周边视野缺损。
  3、视网膜类型:黄斑部视网膜下出血及色素紊乱,中心视力下降。
  上述病变是可逆的。及时停药,合理治疗,多可恢复正常。但也有停药后视力继续恶化,视神经萎缩者。